hi im on mtx, its not nice feeling down but sometimes we exaggerate how things are because we are down,i was not in a good place either,job loss, death of my husband the stuff we carry around with us in our heads and blamed being put on so many meds as that was when all my feelings came to a head but it turned out i was menopausal plus r.a and i felt really bad misrable bit depressed etc,it floored me i was not able to do what i used to which got to me,the symtoms are much the same ie.tired moody etc,i did go to the rehumy about how i felt it scared me i admit but they were really good they helped me go through the list and sort each thing in turn,have a word thats the advice i would suggest it works and remember someone will be there to help even if it feels mega it can be sorted,look positive and talk to someone about how you feel.even if they dont understand just to listen can help,i found my good friend was great she had no idea what i was on about but nodded and grunted in the right places and i actually listened to myself and decided to go down the what positives i had not the negatives, takes time,i still have a rant off and on,talk to your doctor firstly for advice maybe the meds need reviewed,15yrs is a long time, all the best,dorothy.